ANTIBIOPROPHYLAXIS AND ANTIBIOTHERAPY IN ABDOMINAL SURGERY –  SHORT REVIEW

Marina Leontescu; Octavian Andronic; Dan Nicolae Păduraru; Alexandra Bolocan; Daniel Ion

doi:10.33695/rjcr.v2i1.23

Marina Leontescu 1The University of Medicine and Pharmacy ”Carol Davila”, Bucharest, Romania
Octavian Andronic 1The University of Medicine and Pharmacy ”Carol Davila”, Bucharest, Romania 2Emergency University Hospital of Bucharest, Romania
Dan Nicolae Păduraru 1The University of Medicine and Pharmacy ”Carol Davila”, Bucharest, Romania 2Emergency University Hospital of Bucharest, Romania
Alexandra Bolocan 1The University of Medicine and Pharmacy ”Carol Davila”, Bucharest, Romania 2Emergency University Hospital of Bucharest, Romania
Daniel Ion 1The University of Medicine and Pharmacy ”Carol Davila”, Bucharest, Romania 2Emergency University Hospital of Bucharest, Romania

DOI: https://doi.org/10.33695/rjcr.v2i1.23

Keywords: infection, antibioprophylaxis, abdominal surgery, antibiotics

Abstract

Surgical site infection (SSI) represents a concerning for all surgeons because both the unfavorable impact on health care costs and risk factors that increase the durations of wound healing and SSI rate. A review of PubMed, Scopus and Google Scholar has been made. The keywords used were related to surgical site infection prevetion. SSIs have a raised incidence in abdominal surgery because of the fact that many types of bacterias live in the gastrointestinal tract and during a surgical procedure some may escape and cause an infection. There is a high risk of postoperatory infections in gastric surgery due to intestinal anastomoses which are predisposed to leakage. In hernia repair surgery there is a higher rate of SSIs than expected for a clean procedure, and one risk factor may be represented by the prosthetic device used. On the other hand, in laparoscopic cholecystectomy, there is a very low risk of SSI and antibioprophylaxis is not recommended. But the most contaminated procedure with the highest risk of infectious complications is colorectal surgery, which requieres a combination of antibiotics because of the numerous types of microorganism. Abdominal surgery comprises different techniques and involves most elements of the gastrointestinal tract. Some procedures need antibiotic prophylaxis and in others antibiotic administration is even prohibited. The most effective antibiotics are first and second-generation cephalosporins.

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