ACROMEGALY - RELATED OSTEOPOROSIS
Secondary osteoporosis includes modern causes as obesity or type 2 diabetes mellitus, but also acromegaly. The main skeletal anomalies are represented by vertebral fractures which are more often of less clinical severity, but in association with Growth Hormone (GH) excess and time of hyper-secretion exposure, even persistent when pituitary disease is controlled. Dual-Energy X-Ray Absorptiometry (DXA) which is the golden standard of osteoporosis diagnosis might not be helpful and might not reflect the co-presence of osteoporotic fractures. We introduce a case of acromegaly in an adult non-hypogonadic acromegalic man which was accidentally diagnosed during somatotropinoma evaluation. In present case, the patient had a vertebral fracture a low BMD according to osteoporosis criteria despite male sex and lack of central hypogonadism or of diabetes mellitus.