SPLENECTOMY FOR SPLENIC HISTIOCYTOSIS - CASE PRESENTATION AND REVIEW OF LITERATURE
Abstract
Langerhans cell histiocytosis (HCL) is a pathological condition defined by the excess production of histiocytes, a type of dendritic cells involved in the immune response, which is sometimes associated with hematological diseases such as leukemias. In terms of incidence, this condition does not occur by the routine in medical practice, most cases being discovered accidentally. The presented case describes a 47-year-old woman with isolated splenic HCL who manifested clinically repeated pain in the left hypochondrium. The computer tomography described nodular lesions with multiple localization in the spleen. The histopathological and immunohistochemical results, however, provided the diagnosis of certainty , this being isolated splenic HCL. The surgical intervention performed was splenectomy, with favorable early and late postoperative evolution. The patient does not show clinical and paraclinical changes during the periodical controls during the 7 years since the surgical intervention. The early diagnosis and the surgical intervention represent complete solution of these types of cases.
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